Skin lesions associated with porokeratosis can be bothersome. Thankfully, there may be a new option to help reduce and prevent porokeratosis lesions. Read on to learn about Lovastatin/Cholesterol cream.
What is Porokeratosis?
Porokeratosis is a rare skin disorder that usually appears on the skin as small round patches with a ridged border. It affects less than 200,000 Americans and it is more common in fair-skinned individuals. It is a life-long, non-contagious skin condition but can progress into skin cancer.
Although the exact cause of porokeratosis has not been determined, several risk factors have been identified. Most of the cases involve previous skin trauma, genetic defects, ultraviolet radiation, suppressed immune system, and autoimmune diseases.
The most common types of porokeratosis include:
- Classic porokeratosis of Mibelli (PM)
- Linear porokeratosis (LP)
- Disseminated superficial actinic porokeratosis (DSAP)
- Non-actinic disseminated superficial porokeratosis (DSP)
- Porokeratosis palmaris at plantaris disseminata (PPPD) aka porokeratosis of Mantoux
- Punctate porokeratosis (PP)
They differ in appearance, location in the body, age of onset, and risk by gender.
Identification of porokeratosis is done by examining the appearance of the lesion and performing a biopsy from the raised border part of the lesion. This is to check for the presence of cornoid lamella, the hallmark structure of cells found in all types of porokeratosis.
How is Porokeratosis treated?
Treatment of porokeratosis is aimed to address the symptoms, such as itchiness and pain, and to reduce the progression or size of lesions. Benign lesions are monitored for malignancy. The doctor may prescribe topical (applied on the skin) or systemic (into the bloodstream) medications. Removal of lesions can be done by cryotherapy (uses freezing temperature), laser, dermabrasion (exfoliation), and electrodessication (uses electric current).
What is topical Lovastatin/Cholesterol? How will It help improve porokeratosis?
Lovastatin is known as a lipid-lowering drug but is also proven to be effective against certain skin conditions because of its anti-inflammatory, immunomodulatory, antioxidant, and possibly, anti-cancer effects. Cholesterol has moisturizing effects on the skin and is used in cosmetics. However, the combination of lovastatin and cholesterol as a topical treatment appears to affect porokeratosis by replenishing cholesterol, an important element in preventing the genetic mutation that causes this rare skin disorder.
Topical Lovastatin/Cholesterol is a well-tolerated treatment for porokeratosis that targets its initiation and progression, according to the Journal of American Academy of Dermatology. It has no reported adverse effects.
Where to get topical Lovastatin/Cholesterol?
Lovastatin/Cholesterol cream or ointment is only available as a custom-made preparation from a compounding pharmacy. Talk to your healthcare provider and ask about topical options for porokeratosis or you can drop by The Compounding Center to chat with one of our knowledgeable and friendly pharmacists about topical lovastatin/cholesterol.
For more information about topical Lovastatin/Cholesterol,
Text or Call The Compounding Center today at
703-779-3301
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