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Low-Dose Naltrexone (LDN): A Useful Agent for Autoimmune Disease?

LDN for autoimmune disease

Naltrexone is a medication that treats opioid addiction, but at very low doses, it can also improve symptoms of autoimmune disease.

How can LDN help autoimmune disease? 

Even though studies are limited, LDN has been used in some inflammatory autoimmune conditions like Lyme disease, rheumatoid arthritis, Alzheimer’s, fibromyalgia, and multiple sclerosis (MS).

Inflammation is a hallmark of autoimmune diseases, and LDN helps fight infection in a few ways. By increasing endogenous opioids (“happy hormones”) in the nervous system, LDN not only reduces pain and inflammation, but also increases healing and slows cell growth. LDN also helps reduce the effects of cells and proteins that promote inflammation.

Traditional drugs for treating autoimmune disease are effective to varying degrees but carry potential for serious side effects. An advantage of LDN is that because of the low dose, side effects are minimal. The most common side effects include:

  • Vivid dreams or nightmares
  • Headache
  • Nausea
  • Constipation
  • Diarrhea
  • Insomnia
  • Fatigue

To help reduce the risk of side effects, we recommend gradually moving up to the appropriate dose for you. Usually side effects disappear quickly.

How can you try LDN?

Scientific literature is important for understanding how well LDN works, but first-hand accounts from actual patients are also valuable. On the LDN Research Trust website, you will find accounts of patients’ experiences using LDN for autoimmune disease.

The Compounding Center in Leesburg, VA prepares immediate-release LDN tablets with no fillers or common allergens like gluten, lactose, or dyes.

If you live in any of the states we’re licensed in, our trained pharmacy staff will compound your specific LDN dose with a prescription from your doctor. We even ship them to you if you can’t make it to the store!

Click here to get a quote.