How Low-Dose Naltrexone May Help Promote Weight Loss

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How Low-Dose Naltrexone May Help Promote Weight Loss

LDN may help promote weight loss

“I really need to lose weight.”

How many times have you made that comment to yourself? Maybe you’ve been saying it more often lately.

Sure, incorporating more activity and healthful eating into your life is always the best initial approach, but sometimes you might need more help to drop the pounds.

Scientists and doctors believe a medication called low-dose naltrexone (LDN) may help promote weight loss. Keep reading to find out how.

What is Naltrexone?

Naltrexone is a drug that was originally approved by the Food and Drug Administration to treat heroin and opioid addiction.

Naltrexone is an opioid antagonist. That means it blocks opioid receptors so that the actual opioids can’t latch on. Without that contact, the person won’t feel the expected “high.”

How Does Naltrexone Affect Your Body Weight?

Scientists and doctors also know that naltrexone can help with weight loss. In fact, the medication Contrave is actually standard-dose naltrexone combined with an antidepressant called buproprion. Together, these two medications impact eating behaviors and promote weight loss.

Scientists eventually realized that LDN may provide weight loss benefits as well, but with significantly less risk of toxicity.

Is It True That Low-Dose Naltrexone (LDN) May Help Promote Weight Loss?

Very few clinical trials and scientific studies on LDN have been conducted. Much of the information we know about LDN comes from scientists like Dr. Andre Lev-Weissberg, Professor of Medicine at the University of Illinois.

In a talk at the 2014 LDN Conference, Dr. Lev-Weissberg spoke about LDN properties that help promote weight loss:

Restores natural endorphins and dopamine

Dopamine and endorphins like serotonin are signals that pass throughout the body and affect your mood, sense of pleasure, and sense of well-being. When certain endorphins are low, you may feel depressed and anxious.

Depression and anxiety are commonly linked to obesity. These mood disorders also make it difficult for people to lose weight because they may not have enough motivation or energy to exercise well and eat healthfully.

Depression and anxiety medications can also cause weight gain.

By restoring the body’s natural balance of dopamine and endorphins, LDN helps improve mood so that individuals can take better control of their weight.

Restores effective sleep

Not getting enough sleep is also a culprit when it comes to weight gain and inability to lose weight. LDN uses your body’s circadian rhythm to restore natural sleep patterns so that you get better sleep.

Getting adequate sleep is critical for maintaining a healthy weight.

Improves satiety (feeling full or satisfied)

Appetite is something that many people struggle with at some point in their lives. When your body has a hard time feeling full, you are more likely to overeat and eat poorer quality food, which can lead to more weight gain.

LDN improves your body’s sense of fullness so that you have more control over your appetite.

Decreases sugary cravings

Remember those dopamine signals that make us feel happy and euphoric? Without enough dopamine, you may feel anxious, depressed, or just all-around “down.”

To replace those once-happy feelings, the body begins to crave sugar and carbs.

LDN helps decrease those sugar cravings by restoring the body’s natural balance of dopamine. Less cravings for unhealthy foods means less weight gain.

Decreases inflammation

One of the biggest and most well-known benefits of LDN is its effect on inflammation. LDN is commonly used to treat inflammatory conditions such as psoriasis, Crohn’s disease, and chronic pain.

Inflammation can lead to insulin resistance, diabetes, and heart disease, all of which promote weight gain and obesity. By reducing inflammation, LDN helps prevent extreme weight gain and the poor health outcomes associated with obesity.

How Can I Try Low-Dose Naltrexone (LDN)?

As scientists continue to learn more about LDN, more benefits related to weight loss may be discovered.

While the knowledgeable pharmacists at The Compounding Center do our best to share with you the most accurate scientific information, we also understand that first-hand accounts from actual patients are also valuable.

On the LDN Research Trust website, you will find accounts of patients’ experiences LDN to manage their conditions. We encourage you to talk to your doctor about whether LDN might be appropriate for you to try.

If you live in any of the states we’re licensed in, our trained pharmacy staff will compound your specific LDN dose with a prescription from your doctor.

The Compounding Center in Leesburg, VA prepares LDN as immediate-release pills with no fillers or binders to interfere with the drug’s absorption.  Plus, you can be sure we take your allergies and dietary concerns into consideration.  We make sure our compounded LDN pills are free of common allergens like gluten, lactose, and dyes.

We’ll even ship it to you if you can’t get to the store!

Give us a call to get a quote.

The Compounding Center

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