Have you been struggling with constant itching and pain from psoriasis? Now, there may be promising relief for those symptoms.
Psoriasis is a chronic inflammatory skin condition that causes dry, itchy, flaky skin. The itching and flaking can sometimes feel unbearable! Due to intense dryness, the skin can even crack and bleed. Joints can also become painful.
Psoriasis used to be a condition that dermatologists (skin doctors) struggled to treat effectively, until recently. Low-dose naltrexone (LDN) has commonly been used orally to treat autoimmune disorders, such as Crohn’s Disease. Now, it appears that LDN could be an effective topical (on the skin) treatment for the itching, flaking, and painful skin associated with psoriasis.
How Does Low-Dose Naltrexone (LDN) Reduce Psoriasis Symptoms?
Remember that psoriasis is an inflammatory condition. This means that medications with anti-inflammatory properties may be helpful. At low dosage levels, naltrexone has anti-inflammatory properties. This makes LDN is a potential treatment for psoriasis.
Some psoriasis symptoms, such as itching and flaky skin, are also associated with pain. That’s because psoriasis causes a change in how opioid receptors (pain receptors) are expressed in the body.
Naltrexone works by blocking opioid receptors so that they don’t have the opportunity to cause pain.
What Does Science Say about Topical Low-Dose Naltrexone (LDN) and Psoriasis?
Unfortunately, there are no large-scale studies on the effect of topical LDN on psoriasis. However, there have been positive results from one study evaluating the effect of topical LDN on several different chronic itching conditions.
In this study, more than 70% of patients suffering from severe itching experienced a significant reduction of itching 15-30 minutes after applying topical LDN. This effect lasted from 2-6 hours.
How Can I Try Topical Low-Dose Naltrexone (LDN) for My Psoriasis?
While the knowledgeable pharmacists at The Compounding Center do our best to share with you the most accurate scientific information, we also understand that first-hand accounts from actual patients are also valuable.
On the LDN Research Trust website, you will find accounts of patients’ experiences using topical LDN to manage their psoriasis symptoms. We encourage you to talk to your doctor about whether topical LDN might be appropriate for you to try.
If you live in any of the states we’re licensed in, our trained pharmacy staff will compound a customized LDN cream with a prescription from your doctor. We’ll even ship it to you if you can’t get to the store!
Give us a call to get a quote.
The Compounding Center
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